Leadership

President
Laurence
Tiennot-Herment
Chief Executive Officer
Frédéric Revah, Ph.D.
Director of Development
Géraldine Honnet, M.D.
Director of Partnerships & Business Development
Alexandre Lemoalle

An accountant by profession, Laurence Tiennot-Herment found herself launched into the world of disease prevention and the various associations working in this field in 1989 as a result of her son’s illness. Having previously worked for the Telethon and AFM in Seine-Maritime, her native region, she joined AFM Board of Directors in 1997. She was elected first Secretary and then Vice-President, before taking the position of President of AFM in 2003. Since 2005, she has also been President of the Institut de Myologie, and of Genethon since 2009. In addition to her responsibilities within AFM and its “operational branches”, Laurence Tiennot-Herment is Director of the public interest group Genopole, and of the Imagine Foundation, as well as sitting on the management committee of the scientific interest group Institut des Maladies Rares.

Frédéric Revah is Chief Executive Officer of Genethon and President of YposKesi, one the largest industrial platforms for pharmaceutical production of gene- and cell-therapy products created in Nov. 2016 by AFM-Telethon and Bpifrance. Frédéric Revah has more than twenty five years’ experience in biotech and pharmaceutical industry, where he held several corporate managerial positions, as well as in academic research. He obtained his Ph.D. at the Institut Pasteur / Université Paris V, and graduated from the Ecole Polytechnique engineering school.

Before joining Genethon, Géraldine Honnet served as Head of Clinical Development in Infectious Diseases at Transgene, International Project Manager at Janssen-Cilag and Medical Director at Parexel International.
She has also worked at Hospital Saint-Louis as a Monitor for Clinical Studies and Investigator, for the ANRS (National Agency for AIDS Research) and the pharmaceutical industry.
Géraldine has graduated from Necker Children’s Hospital Medical School (Paris).

Alexandre Lemoalle has more than twenty years experience in the pharma industry.  Before joining Genethon he had different functions in Finance within Sanofi and then as General Manager of subsidiaries and VP Mergers & Acquisitions for the group Sanofi. He then accompanied biotechs in their development and advised some Funds in their investments in Health sector. Alexandre is graduated from l’Institut Supérieur de Gestion (ISG).

Director, Gene Therapy Technology and CMC Development
Matthias Hebben, Ph.D.
Director of neuromuscular strategy
Serge Braun, PharmD, PhD

Before joining Genethon in 2013, Matthias Hebben has worked with pharmaceutical and biotech companies such as VIRBAC, INTERVET-SCHERING PLOUGH, and VIVALIS, where he held several R&D and management positions related to the Virology field and technologies for Recombinant Virus biomanufacturing. He obtained his PhD in 2001 from the University of Nice-Sophia Antipolis, France.

Serge Braun is currently Scientific Director of AFM-Telethon (the French Muscular dystrophy Association acting in innovative therapies of rare diseases) and President of Genosafe (a CRO company dedicated to QC of biotherapeutic products).

He prior had 10 years of experience in the neuromuscular diseases field in the academic sector (Univ. Strasbourg France and USC Neuromuscular Center, Los Angeles) ; and 10 years in the biotechnology sector (Vice-President Research of Transgene SA, Gene therapy biotech company) were he developed his career in the field of gene therapy of genetic diseases and of immunotherapeutics.

He was co-founder of Neurofit (a contract research organization specialized in preclinical testings of both the central and the peripheral nervous system), Vice-President of Alsace BioValley (the tri-national initiative, non-profit making organization, for the development of a major biotech cluster in Europe).

He also serves as advisor for Venture Capital companies and bioclusters.

Board

Chairman
Laurence
Tiennot-Herment
Vice-Chairman
Claude Allary
Treasurer
Marc Bouillet
Secretary
Marie-Christine Ouillade

Laurence Tiennot-Herment, President of AFM and the Institut de Myologie. An accountant by profession, Laurence Tiennot-Herment found herself launched into the world of disease prevention and the various associations working in this field in 1989 as a result of her son’s illness. Having previously worked for the Telethon and AFM in Seine-Maritime, her native region, she joined AFM Board of Directors in 1997. She was elected first Secretary and then Vice-President, before taking the position of President of AFM in 2003. Since 2005, she has also been President of the Institut de Myologie, and of Genethon since 2009. In addition to her responsibilities within AFM and its “operational branches”, Laurence Tiennot-Herment is Director of the public interest group Genopole, and of the Imagine Foundation, as well as sitting on the management committee of the Maladies Rares Foundation.

Claude Allary, is a consultant and executive coach with Life Sciences industrial and financial companies. After 14 years’ experience with the International Pharmaceutical Industry, followed by 21 years in technology and strategy consulting, he now devotes his time to innovative companies and Patient Associations, and participates to on-going debates about prospective and strategy via articles and conferences.

Marc Bouillet, Consultant, Former Director of Government Affairs and Health Economics at Johnson & Johnson Medical Devices & Diagnostics, former Executive Officer of AFM.He is also treasurer of the Institut de Myologie.

Marie-Christine Ouillade, member of the Board of Directors of AFM, engineer and member of the Biomedicine Agency Advisory Council.

Member
Pierre-Etienne Bost
Member
Jean-Pierre Lamorte
Member
Claude Le Pen
Member
Nathalie Triclin-Conseil

Pierre-Etienne Bost, Executive Director of the Académie des Technologies, Member of the Conseil Supérieur de la Recherche et de la Technologie, former Director of Research in the pharmaceutical industry and at the Institut Pasteur.He is also President of Genatlantic.

Jean-Pierre Lamorte, engineer in the field of telecommunications, has been engaged in the battle of the association against the illness of his son in 1993, at the time of diagnosis. After participating in the creation of the Delegation of the AFM-Telethon for the Hauts de Seine, the creation of the Interest Group Duchenne Becker, he joined the Board of Directors of AFM-Telethon in 2005 as Secretary and Treasurer then Vice President in 2008, will also sit on the Board of the Institute of Myology in 2007/2008 and the bord of Genethon since 2007.
From 2009 to 2014, he held the position of Director for the Patient and Family support.

Claude Le Pen, Professor of Health Economics at Université Paris – Dauphine – LEGOS.

Nathalie Triclin-Conseil, mobilized very early in the fight against rare diseases, founding and presiding for more than 10 years the Association of Patients of Fabry Disease (APMF). This strong experience allowed her to represent the patients in different instances. In 2006, she wanted to give a new dimension to her activism and joined the Alliance Rare Diseases. In 2012 as Vice-president but primarily since the 16th of October 2016 as President of the collective of more than 210 associations, she brings the voice of people affected by rare diseases in the monitoring committee of rare disease plans, France Assos Santé and l’Agence Française de Biomedicine.

Scientific leadership

Head of Inserm Unit
Anne Galy, Ph.D.
Head of the Progressive Dystrophy Laboratory
Isabelle Richard, Ph.D.
Head of the Congenital Myopathies Laboratory
Ana Buj-Bello, Ph.D.
Researcher
Federico Mingozzi, Ph.D.

Anne Galy heads an INSERM Research Group at Genethon, as well as a hematopoietic gene therapy translational program. She is qualified in pharmacy and received her doctorate in Immunology from Université de Lyon (1989). She worked in the USA biotech sector in Palo Alto (California) before becoming a Professor of Immunology at the School of Medicine and at the Karmanos Cancer Institute at the Wayne State University in Detroit, Michigan. In 2001, she joined INSERM as a Research Director. She currently runs INSERM Unit 951 at Genethon, which has links with Université d’Evry Val d’Essonne and the Ecole Pratique des Hautes Etudes. This research laboratory develops innovative treatments for diseases of the immune system and blood, and is particularly interested in mechanisms for immunization by viral gene transfer. Anne Galy has published more than 90 articles in international scientific journals.

Isabelle Richard joined Genethon in 1996 and heads a research group which is developing innovative muscular dystrophy treatments and investigating genetics and the physiopathological mechanisms of genetically-inherited diseases.
She is also in charge of a translational muscular gene therapy program.
She is Director of Research at the CNRS, and obtained her PhD in Human Genetics from Université de Paris 7 (1996).
She is taking part in a European project called NMD-chip and has had 110 articles published in international scientific journals.

Ana Buj Bello heads a research team at Genethon working on neuromuscular diseases, as well as a translational program investigating gene therapy for the treatment of myotubular myopathy. She received her degree in Medicine and Surgery from the University of Lleida, Spain, and a PhD in Neurosciences from the University of St Andrews (Great Britain). She also obtained a diploma in Myology from the University of Pierre et Marie Curie, France. Having done a post-doctorate at the Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, where she worked for several years on the pathophysiology of myotubular myopathy, she joined the INSERM in 2004 and has worked at Genethon since 2009. Ana Buj Bello has published about 40 articles in international scientific journals and received the 2015 Outstanding New Investigator Award from the American Society of Gene & Cell Therapy (ASGCT).

Federico Mingozzi heads a research group at Genethon which is working on the development of liver-targeted gene therapies for inherited diseases and on the characterization of immunity and tolerance in gene transfer. He is also Associate Professor at the University Pierre and Marie Curie in Paris.

He received his Biology degree and Ph.D. In Biochemistry and Molecular Biology from the University of Ferrara, Italy. He also obtained a Master in Business Administration from Drexel University, United States. He spent over ten years in the United States at the Children’s Hospital of Philadelphia and University of Pennsylvania where he was involved in the early development of gene therapies based on the adeno-associated virus (AAV) vector platform. In his research, he characterized the mechanisms of immune tolerance induction mediated by AAV vector liver gene transfer. More recently he focused on the clinical development of AAV vector-based gene therapies for inherited diseases and on the study of immune responses directed against AAV vectors in human trials. He contributed to several first-in-human AAV gene transfer clinical trials for indications including hemophilia B, Leber’s Congenital Amaurosis, and lipoprotein lipase deficiency. He contributed to about 80 publications, including original research articles, reviews and commentaries, and book chapters.

Director, Gene Therapy Technology and CMC Development
Matthias Hebben, Ph.D.
Head of Applied Vector Studies
Otto-Wilhelm Merten, Ph.D.

Before joining Genethon in 2013, Matthias Hebben has worked with pharmaceutical and biotech companies such as VIRBAC, INTERVET-SCHERING PLOUGH, and VIVALIS, where he held several R&D and management positions related to the Virology field and technologies for Recombinant Virus biomanufacturing. He obtained his PhD in 2001 from the University of Nice-Sophia Antipolis, France.

Otto-Wilhelm Merten joined Genethon in 1997 and is currently in charge of the Applied Vector Studies group which helps innovate and optimize vector production. A Doctor of Biotechnology (Vienna, Austria), he has worked at the Institut Pasteur (Paris, France) as well as at the Sandoz Research Institute (Vienna, Austria). He has helped develop virus production processes, first for vaccination (influenza, poliomyelitis, rabies), and them for treatment applications. Otto-Wilhelm Merten has had 112 articles published in international scientifc journals and is Editor in Chief of Cytotechnology. He has also been a member of the ESACT (European Society for Animal Cell Technology) Executive Committee for 16 years (including four years as President from 2001 to 2005).