Genethon I – Mapping the Human Genome

J. Weissenbach, I. Chumakov, D. Cohen et J. Dausset

J. Weissenbach, I. Chumakov, D. Cohen et J. Dausset











During this initial period, Genethon made its mark by becoming the first in the world to publish a map of the human genome. This map, an unprecedented discovery, was offered to the scientific community in 1992, and advanced the human genome sequencing project by six years.

At this time, three major projects were being conducted at Genethon:

  • a physical map of the human genome, directed by Daniel Cohen;
  • a genetic map, directed by Jean Weissenbach;
  • and an inventory of gene transcripts for muscle and nerve cells, directed by Charles Auffray.

On September 18, 1992, the journal Cell published Genethon’s first physical map covering half of the human genome.

On October 1, the journal Nature published Genethon’s first map of a chromosome, chromosome 21.

On October 29, the laboratory used the same journal to publish an article about the first markers on the genetic map (814 markers).

These three world Firsts confirmed the laboratory’s outstanding reputation, and placed France on top in the world genetic research stakes.