Publications scientifiques 2014

  1. 1. Allenbach, Y., W. Chaara, et al. (2014). « Th1 response and systemic treg deficiency in inclusion body myositis. » PLoS One 9(3): e88788.
  2. 2. Basner-Tschakarjan, E. and F. Mingozzi (2014). « Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions. » Front Immunol 5: 350.
  3. 3. Brayet, J., F. Zehraoui, et al. (2014). « Towards a piRNA prediction using multiple kernel fusion and support vector machine. » Bioinformatics 30(17): i364-i370.
  4. 4. Childers, M. K., R. Joubert, et al. (2014). « Gene therapy prolongs survival and restores function in murine and canine models of myotubular myopathy. » Sci Transl Med 6(220): 220ra210.
  5. 5. Chuah, M. K., I. Petrus, et al. (2014). « Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates. » Mol Ther 22(9): 1605-1613.
  6. 6. Cire, S., S. Da Rocha, et al. (2014). « Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo. » PLoS One 9(7): e101644.
  7. 7. Clermont, D., S. Santoni, et al. (2014). « Assessment of DNA encapsulation, a new room-temperature DNA storage method. » Biopreserv Biobank 12(3): 176-183.
  8. 8. Corre, G., D. Stockholm, et al. (2014). « Stochastic fluctuations and distributed control of gene expression impact cellular memory. » PLoS One 9(12): e115574.
  9. 9. Corre, G., D. Stockholm, et al. (2014). « Variabilité non-génétique dans les cultures cellulaires ». Culture de cellules animales, 3ème édition. G. Barlovatz-Meimon and X. Ronot, Lavoisier S.A.S. / Inserm.
  10. 10. Denard, J., C. Jenny, et al. (2014). « Different protein composition and functional properties of adeno-associated virus-6 vector manufactured from the culture medium and cell lysates. » Molecular Therapy — Methods & Clinical Development 1.
  11. 11. Evila, A., A. Vihola, et al. (2014). « Atypical phenotypes in titinopathies explained by second titin mutations. » Ann Neurol 75(2): 230-240.
  12. 12. Ferrand, M., A. Galy, et al. (2014). « A dystrophic muscle broadens the contribution and activation of immune cells reacting to rAAV gene transfer. » Gene Ther.
  13. 13. Fraysse, B., A. Vignaud, et al. (2014). « Acute effect of androgens on maximal force-generating capacity and electrically evoked calcium transient in mouse skeletal muscles. » Steroids.
  14. 14. Goddard, M. A., E. Burlingame, et al. (2014). « Gait characteristics in a canine model of X-linked myotubular myopathy. » J Neurol Sci 346: 221-226.
  15. 15. Holic, N., A. K. Seye, et al. (2014). « Influence of Mildly Acidic pH Conditions on the Production of Lentiviral and Retroviral Vectors. » Hum Gene Ther Clin Dev 25(3): 178-185.
  16. 16. Ingrao, D., S. Majdoul, et al. (2014). « Concurrent measures of fusion and transduction efficiency of primary CD34+ cells with human immunodeficiency virus 1-based lentiviral vectors reveal different effects of transduction enhancers. » Hum Gene Ther Methods 25(1): 48-56.
  17. 17. Jeanson-Leh, L., J. Lameth, et al. (2014). « Serum Profiling Identifies Novel Muscle miRNA and Cardiomyopathy-Related miRNA Biomarkers in Golden Retriever Muscular Dystrophy Dogs and Duchenne Muscular Dystrophy Patients. » Am J Pathol.
  18. 18. Lawlor, M. W., M. G. Viola, et al. (2014). « Differential Muscle Hypertrophy Is Associated with Satellite Cell Numbers and Akt Pathway Activation Following Activin Type IIB Receptor Inhibition in Mtm1 p.R69C Mice. » Am J Pathol 184(6): 1831-1842.
  19. 19. Le Guiner, C., M. Montus, et al. (2014). « Forelimb Treatment in a Large Cohort of Dystrophic Dogs Supports Delivery of a Recombinant AAV for Exon Skipping in Duchenne Patients. » Mol Ther.
  20. 20. Mavilio, F. (2014). « Repairing without cutting: a safer alternative to gene correction? » Mol Ther 22(4): 690-691.
  21. 21. Merten, O. W., W. A. M. Bakker, et al. (2014). « Virus production under suspension conditions ». Industrial scale suspension culture of living cells. H. P. Meyer and D. Schmidhalter, Wiley-VCH Vrlag GmbH & Co. KGaA: 503-554.
  • 22. Merten, O. W., M. Schweizer, et al. (2014). Production and purification of viral vectors and safety considerations related to their use. Advanced textbook on gene transfer, gene therapy and genetic pharmacology. D. Scherman, Imperial College Press, London/U.K.: 493-515.
  • 23. Merten, O. W., M. Schweizer, et al. (2014). « Manufacturing of viral vectors for gene therapy: part I. Upstream processing. » Pharma. Bioprocess. 2(2): 183-203.
  • 24. Merten, O. W., M. Schweizer, et al. (2014). « Manufacturing of viral vectors: part II. Downstream processing and safety aspects. » Pharma. Bioprocess. 2(3): 237-251.
  1. 25. Moiani, A., J. D. Suerth, et al. (2014). « Genome-wide analysis of alpharetroviral integration in human hematopoietic stem/progenitor cells. » Genes (Basel) 5(2): 415-429.
  2. 26. Monjaret, F., N. Bourg, et al. (2014). « Cis-splicing and Translation of the Pre-Trans-splicing Molecule Combine With Efficiency in Spliceosome-mediated RNA Trans-splicing. » Mol Ther.
  3. 27. Mouisel, E., K. Relizani, et al. (2014). « Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle. » Am J Physiol Regul Integr Comp Physiol 307(4): R444-454.
  4. 28. Nathwani, A. C., U. M. Reiss, et al. (2014). « Long-term safety and efficacy of factor IX gene therapy in hemophilia B. » N Engl J Med 371(21): 1994-2004.
  5. 29. Neildez-Nguyen, T. M., J. Bigot, et al. (2014). « Hypoxic culture conditions enhance the generation of regulatory T cells. » Immunology.
  6. 30. Relizani, K., E. Mouisel, et al. (2014). « Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy. » Mol Ther.
  7. 31. Revah, F. (2014). « Genethon: patient-empowered research. » Informa Healthcare: 1-6.
  8. 32. Rodriguez, E. G., R. Lefebvre, et al. (2014). « Phosphoinositide substrates of myotubularin affect voltage-activated Ca(2)(+) release in skeletal muscle. » Pflugers Arch 466(5): 973-985.
  9. 33. Rouillon, J., A. Zocevic, et al. (2014). « Proteomics profiling of urine reveals specific titin fragments as biomarkers of Duchenne muscular dystrophy. » Neuromuscul Disord.
  10. 34. Sarwal, A., M. S. Cartwright, et al. (2014). « Ultrasound assessment of the diaphragm: Preliminary study of a canine model of X-linked myotubular myopathy. » Muscle Nerve 50(4): 607-609.
  11. 35. Turchiano, G., M. C. Latella, et al. (2014). « Genomic analysis of sleeping beauty transposon integration in human somatic cells. » PLoS One 9(11): e112712.